The vogtkoyanagiharada syndrome vkh is a bilateral, diffuse granulomatous uveitis associated with poliosis, vitiligo, alopecia, and central nervous system and auditory signs. Vogtkoyanagiharadas disease is a rare syndrome that affects tissues with melanocytes like eyes, central nervous system, skin and inner ear. Vogtkoyanagiharada disease vkh disease is a disease that affects several parts of the body, including the eyes, ears, nervous system, and skin. The immune response in vkh syndrome most likely is directed against antigens. Vogtkoyanagiharada disease vkhd, initially described as an uveomeningoencephalitic syndrome, is a constellation of clinical symptoms. Uveomeningoencephalitic syndrome vogtkoyanagiharanda vkh is an unusual syndrome with important neurological complications and has not. The signs and symptoms of vkh disease are caused by chronic inflammation of melanocytes. Pdf vogtkoyanagiharadas syndrome and its multisystem. The term vogtkoyanagiharada disease was coined by bruno and mcpherson 8 to encompass the previous reported uveomeningeal syndromes as one widespectrum entity. Vogtkoyanagiharadas syndrome is a rare disease that affects tissues containing melanocytes, such as the eyes, central nervous system, inner ear and skin. Some ethnic groups have a higher probability of developing the disease, including asians, indians and latin americans and females are affected more often. The vogt koyanagi harada syndrome vkh is a bilateral, diffuse granulomatous uveitis associated with poliosis, vitiligo, alopecia, and central nervous system and auditory signs.
Pdf a u g u s t 3 1, 2 0 1 0 v o l u m e 9 n u m b e r 1 6 contemporary. Pdf vogtkoyanagiharada syndrome is a bilateral, chronic, diffuse granulomatous panuveitis frequently associated with neurological. Make a photocopy of the completed answer form for your own files and mail the. Differential diagnosis includes other causes of posteriorpanuveitis, such as sympathetic ophthalmia, uveal effusion syndrome, posterior scleritis. The vogtkoyanagiharada vkh syndrome is an uncommon disorder characterized by uveitis and neurologic and cutaneous abnormalities, including tinnitus, vertigo, headache, meningoencephalitis.
Vkh syndrome may be defined as a bilateral, chronic, granulomatous panuveitis associated with systemic manifestations that may affect. Vogtkoyanagiharada syndrome vkhs is a rare multisystemic disease which probably has autoimmune etiology. Utility of existing vogtkoyanagiharada syndrome diagnostic criteria at initial. Vogt koyanagiharada syndrome vkh is a severe bilateral. Vogtkoyanagiharada syndrome vkh is a severe bilateral. Vogtkoyanagiharada disease genetic and rare diseases. Vogtkoyanagiharadas syndrome and its multisystem involvement. A case report on vogtkoyanagiharada disease seen at a.
Here, we describe a unilateral case of vkh disease. Vogtkoyanagiharada syndrome uveomeningoencephalitic. To evaluate clinical and demographic features of vogt kayanagi harada disease vkh disease in turkish patients and compare them with previously. Vogtkoyanagiharada vkh disease is an immunemediated. Vogtkoyanagiharada disease genetic and rare diseases nih.
Uveomeningoencephalitic syndrome vogtkoyanagiharada. Melanocytes are specialized cells that produce a pigment called melanin. Article information, pdf download for vogtkoyanagiharada syndrome. It affects primarily asians, indians and latin americans and also women.
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